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Researchers develop a hairpin-shaped bicyclic peptide to fight cancer – News-Medical.net

The inhibition of pathological protein-protein interactions is a promising approach for treating a large number of diseases, including many forms of cancer.

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The inhibition of pathological protein-protein interactions is a promising approach for treating a large number of diseases, including many forms of cancer. A team of researchers has now developed a bicyclic peptide that binds to beta-catenin–a protein associated with certain types of tumor. The secret of their success is the cyclic nature and the hairpin shape of the peptide, which mimics a natural protein structure, they report in the journal Angewandte Chemie.
Because of the extensive protein…

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